(P093) ONE-YEAR OUTCOMES OF K-CLIP TRANSCATHETER ANNULAR REPAIR FOR PATIENTS WITH SEVERE ATRIAL FUNCTIONAL TRICUSPID REGURGITATION

Background: Atrial functional tricuspid regurgitation (AFTR) is a significant type of tricuspid regurgitation (TR) with limited interventional options. The K-Clip™, a novel transcatheter tricuspid annuloplasty device, is a clip-based annular plication approach for TR. The aim of this was to explore the feasibility and effectiveness of transcatheter annular repair with the K-Clip™ for AFTR.

METHODS AND RESULTS: We included patients with severe AFTR who underwent transcatheter annular repair with the K-Clip™ at Zhongshan Hospital during the inclusion period. Baseline data, imaging results, and follow-up data were collected.
All 38 patients (17 males, 73.5±7.4 years of age) underwent successful intervention; the mean procedure time and intervention time were 2.1±1.4 hours and 63.3±8.8 min, respectively, and the mean radian exposure was 1015.2±601.7 mGy. The volume of regurgitation decreased significantly, accompanied by a notable reduction in the effective regurgitation orifice area and tricuspid annulus diameter. TR was significantly reduced after the intervention, with marked improvements in New York Heart Association functional class and Kansas City Cardiomyopathy Questionnaire scores. Remodeling of the right atrium and right ventricle was reversed during follow-up. Three non-cardiovascular deaths were documented, and the rate of adverse events during follow-up was acceptable.

Conclusion: In patients with severe AFTR, transcatheter annular repair with the K-Clip™ was associated with durable TR reduction, as well as positive echocardiographic, clinical, and quality-of-life outcomes.